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Bishop HO, Grieve IC, Chudek JA, Hopkins DW

This form of programmed cell death also participates in the etiology of several human diseases including cancer, neurodegenerative, and autoimmune disorders

Cell Death Differ 22(10):16051617

These are the lines and creases that form as a result of repeated facial expressions such as smiling, frowning, and squinting

Recent studies have elucidated that the immunosuppressive function of MDSCs is intricately regulated by a myriad of complex metabolic pathways, with hypoxia playing a pivotal role in this regulation (109111)