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Absent expansion of AXIN2+ hepatocytes and altered physiology in Axin2CreERT2 mice challenges the role of pericentral hepatocytes in homeostatic liver regeneration

The SOD absence accompanied with the swells of mitochondrial structure and mitochondrial cristae changes, further decreased ATP production and elevated level of oxidative DNA damage can be observed which eventually impact the RPE function

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443 Hepatic lipid remodeling results in a favorable metabolic and inflammatory environment to promote the compensatory proliferation of hepatocytes in subjects with nonalcoholic steatohepatitis (NASH)

& Bauer, B