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Thus, during obesity, adipose tissue is distinguished by increased fibrosis, macrophage infiltration, a pro-inflammatory phenotype, leading to the appearance of insulin resistance through the release of free fatty acids, pro-inflammatory cytokines and adipokines

Patients who are using GLP-1 drugs need to be sure that theyre continuing to eat nutritious, well-balanced diets

European Journal of Endocrinology/European Federation of Endocrine Societies, 168 (5), 10.1530/EJE-12-1037

In some early trials, effects like shorter sleep latency were seen fairly quickly (within hours) after administration

References 1 Journal of Pharmacological SciencesKlicek R et al