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Interestingly, PHGDH also affects tumor biology independently of its effects in serine metabolism, for example, directly interacting with the RNA-binding protein Poly(rC)-binding protein 2 (PCBP2), and inhibiting its proteasomal degradation

Metabolic reprogramming of tumor-associated macrophages using glutamine antagonist jhu083 drives tumor immunity in myeloid-rich prostate and bladder cancers

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Growth-modulating plasma tripeptide may function by facilitating copper uptake into cells