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A systematic review covering topical, oral and IV glutathione concluded that although topical/oral forms show some effect, the quality of evidence is modest and the effects modest too

Further experimental studies and clinical trials are now necessary to document the relative importance of the oxidant stress caused by an altered redox potential associated with an elevation of homocysteine level, in comparison with alternative molecular mechanisms

doi: 10.1111/j.1365-2265.2010.03904.x 47 RaymanMP

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