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The list of drug targets was compiled after combining the outputs of SuperPred and SwissTargetPrediction and removing duplicates, and used as Set A, while epilepsy genes were used as Set B and oxidative stress-related genes were used as Set C

The FTO rs9939609 variant also modulates appetite regulation and fat mass predisposition, affecting how strongly tirzepatide's hunger signals translate into reduced intake

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Furthermore, the review highlights delivery innovations, safety considerations, and translational strategies, thereby providing a theoretical foundation for future research and clinical application of flavonoid-based therapies in AD

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