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The pancreas is a vital organ with two main functions: producing insulin to manage blood sugar (endocrine function) and creating digestive enzymes to break down food (exocrine function)

Endotoxemia Lipopolysaccharide (LPS) is a major component of the outer membrane of all gram-negative bacteria that can trigger the synthesis and release of pro-inflammatory cytokines such as TNF, interleukin 1 (IL-1), and inducible nitric oxide synthase (iNOS) (Zhang et al., 2000

Abdominal pain, nausea, vomiting, diarrhea, and vertigo have also been reported, and one trial found that the incidence of nausea, vomiting, and vertigo was dose-dependent (77)

2025;14(10):e70947