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For example, PAP has been shown to undergo poly(ADP-ribosyl)ation (PARylation) upon heat shock and this post-translational modification inhibits polyadenylation 48

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Therefore, FMT-mediated restoration of gut microbial diversity activates SCFA-GLP-1 axis-driven metabolic reprogramming and bacterial consortia-enhanced barrier repair, synergistically ameliorating diabetic immunometabolic dyshomeostasis through microbiome-pancreatic crosstalk

[5] In Latin America, about 40 percent are estimated to be affected, and this may be as high as 80 percent in parts of Africa and Asia