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A pilot trial on the efficacy of interpersonal social rhythm therapy with quetiapine or placebo in patients experiencing bipolar depression reported that the quetiapine group had higher pro-inflammatory and lower anti-inflammatory cytokines compared to the placebo group [80]

[DOI] [PMC free article] [PubMed] [Google Scholar] 118.Leveque C., Mrakic Sposta S., Theunissen S., Germonpr P., Lambrechts K., Vezzoli A., Bosco G., Lvnez M., Lafre P., Guerrero F., et al