Publications: abstracts, posters and presentations
How 5-amino-1mq fits the broader peptide landscape The metabolic optimization space includes numerous compounds with various mechanisms
The assay demonstrates high sensitivity, as evidenced by its low detection limits (LOD) and quantification (LOQ) of 3 U/L and 1 U/L, respectively
HGF/c-Met signaling is a well-established oncogenic pathway: c-Met is amplified or overexpressed in multiple cancers (gastric, lung, renal, hepatocellular) HGF/c-Met activation promotes tumor cell proliferation, survival, invasion, and metastasis c-Met inhibitors are FDA-approved cancer drugs (cabozantinib, crizotinib, capmatinib) A compound that potentiates HGF/c-Met signaling raises theoretical concerns about promoting tumor growth or transformation with chronic use
Doctors usually determine dosage based on blood test results