Combination approaches addressing multiple mechanisms simultaneously (neuroprotection plus antioxidant plus anti-inflammatory) potentially most effective for moderate disease
L-NAME and BPC 157 regimens and dose application were adjusted according to our previous studies (reviewed Alternatively, to perceive the effect of the given medication itself (without L-NAME), rats received only BPC 157 (total dose 10 g/kg or 10 ng/kg as retrobulbar application in each eye, 1 g/0.1 ml saline/each eye, or 1 ng/0.1 ml saline/each eye) or only saline via retrobulbar application in each eye (0.1 ml/each eye) (as an additional control sham group) at the corresponding time point
Lot-specific identifiers, assay values, and methods are maintained in that record and are not repeated in this product dossier
BPC-157 is a synthetic peptide composed of 15 amino acids, hence the term stable gastric pentadecapeptide. It is a partial copy of a sequence linked to a protein found in gastric juice
In peripheral nerve transection, BPC-157 enhances Schwann cell proliferation and axonal outgrowth, improving nerve conduction recovery velocity
