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Emergency department visits made by patients with sickle cell disease: a descriptive study, 1999-2007

As a reaction to the high variability in intrapatient trough levels, which are associated with worse outcomes (124129), once-daily administered Tac formulations with prolonged drug release have been developed to improve bioavailability and adherence as well as lower intraday fluctuation and peak concentrations (Cmax), as illustrated in Figure 1

While glutathione can be administered at any time of day, strategic timing may enhance results or improve convenience based on individual circumstances and preferences

Lancet 346 , 558560 (1995)

Even when I travel