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S2CID 20350330

Oral delivery of nucleic acid therapeutics: challenges, strategies, and opportunities

Schematic showing how the iron-sulfur clusters-containing protein LIAS enables OGDH and PDH activity by transferring lipoic acid as a cofactor to their enzyme complexes (top left)

For acute injuries, such as muscle strains, ligament damage, or joint pain, some individuals may experience relief within 3 to 7 days of consistent use

Madwani K, Huang HJ, Shelton DN, Fu S, Tsimberidou AM, Piha-Paul SA, Naing A, Hong DS, Karp DD, Andrews DL, Cabrilo G, Kopetz ES , Luthra R, Kee BK, Eng C, Morris VK, Karlin-Neumann GA, Meric-Bernstam F, Janku F