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Improved prediction of peptide detectability for targeted proteomics using a rank-based algorithm and organism-specific data

Other contributing factors include dead skin cell buildup, ingrown hairs from shaving, hormonal changes that affect melanin regulation systemically, and obesity or insulin resistance which can cause acanthosis nigricans

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HCT116 cells are an extensively used human colorectal model that carry a KRAS G13D mutation but retain wild-type TP53 and APC 17