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In a study done in 15 patients with PD, 200 mg of GSH was given intranasally and showed that GSH levels did not only raise, but the levels remained high even 1 hour after administration

Collectively, these shifts not only aggravate intestinal pathology but also contribute to insulin resistance, dyslipidemia, and other cardiometabolic risks, reinforcing the bidirectional relationship between dysbiosis and systemic inflammation

In some extreme cases, there has been evidence of tingling sensation and even chest pains in those lacking B12

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