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Atheroscler Rep

Modulating LOOHs and iron via the the mechanistic target of rapamycin (mTOR) can inhibit ferroptosis in adult mouse cardiomyocytes

In the SURMOUNT-1 trial with 2,539 adults with obesity, participants on the highest tirzepatide dose (15 mg weekly) lost an average of 20.9% of their body weight over 72 weeks

Cytokines Measurement The levels of TNF- and IL-1 in serum and peritoneal lavage fluid collected at 24 h post CLP induction were quantified by Enzime-Linked Immunosorbent Assay (ELISA) using an appropriate commercial kit (R&D Systems, Minneapolis, Canada) according to the manufacturer's instructions

doi: 10.1371/journal.pone.0034152