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Furthermore, 100% m 6 A reduced NanoLuc reporter protein expression by 98% and 99% compared to unmodified RNA when using endosomal and non-endosomal RNA delivery into RAW 264.7 cells [248]

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Four molecule families have peer-reviewed clinical evidence supporting their use in microinfusion delivery

For example, other commercially-available glycerin-based gels, glycerin-derived compounds, conjugated or crosslinked gels, matrices, hydrogels, and polymers, as well as gelatins and their derivatives, alginates, alginate-based gels, and even various native and synthetic hydrogel and hydrogel-derived compounds are all expected to be useful in the otic formulations described herein