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In animal toxicology studies, no significant adverse effects have been observed even at doses far exceeding typical therapeutic ranges

While B12 is naturally present in animal-based foods such as meat, fish, and dairy, many people struggle to get adequate amounts due to dietary restrictions, absorption issues, or certain medical conditions

In many cases, Vitamin B12 supplementation can help alleviate neuropathy-related pain

Doses as high as 2 mg (2,000 g) daily by mouth or 1 mg monthly by intramuscular (IM) injection have been used to treat pernicious anemia without significant side effects (136)

It helps maintain the protective covering of nerves, known as the myelin sheath