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Furthermore, supplementation with L-GSH in T2DM subjects, resulted in maintained levels of reduced GSH ( Figures 4FH ), while the group that received placebo had decreased levels of reduced GSH after 3 months ( Figures 4FH )

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Mechanistically, honey enhances chemotherapeutic efficacy through multiple pathways: inhibition of drug efflux pumps (135), ROS-mediated apoptosis induction (136), and suppression of autophagy via AMPK/mTOR axis modulation (121)

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