The dose of vitamin B12 injection for adults may vary depending on the problem to be treated: Treatment of mild nerve pain : the initial dose is 5,000 IU until pain resolves Treatment of intense nerve pain: the initial dose can be increased to 15,000 IU per day and reduced by the doctor as pain resolves Treatment of pernicious anemia: the dose can vary from 100 to 1000 IU per day and the treatment time varies from person to person
That is more than sufficient for complete tissue recovery
A deficiency can occur for several reasons, such as pernicious anemia (a condition where the body cannot absorb vitamin B12 from the diet), certain medical conditions (e.g., Crohn's disease, celiac disease), surgical removal of part of the stomach or intestine, or strict vegetarian/vegan diets if not adequately supplemented
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Animal evidence