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"It'll have the muscle-boosting, muscle-building effects, but it will promote fluid retention, it will promote osteoarthritis, inflammation, deranged glucose metabolism and increased diabetes risk if she's a susceptible person," she said

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The logic is straightforward: with less food and digestive action in the stomach, the peptide has a clearer and faster path to the intestines where it can exert its effects directly on the gut lining with minimal interference

It remains to be understood the exact mechanisms by which adipocyte-generated ceramides promote lipotoxicity