These contradictory findings of metabolomic studies in different populations could be attributed to several factors
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If you have no erosion or tophi present, uric acid levels should be less than 360 mol/l
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As the medium is usually high in B9 (about 9 mM), we simulated a state of nutrient inadequacy by utilizing a depleted medium with reduced levels of vitamin B9 sourced only from the added serum (34)