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The topical anesthetic on the skin should prevent discomfort from the injection

Katewa A, Suto E, Hui J, Heredia J, Liang J, Hackney J et al (2021) The peptide symporter SLC15a4 is essential for the development of systemic lupus erythematosus in murine models

Researchers isolated and stabilised this fragment to study how the organism shields and repairs itself, and since the late 1990s the Zagreb group led by Sikiri and colleagues has built much of the foundational literature around it (Sikiri et al., 2024)

Arthritis Rheumatol 71(5):766772

Many sensory changes need nothing more than time, so the aim is to do what is proportionate rather than to intervene for the sake of it