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Abstract Alzheimers disease (AD) is a neurodegenerative disease characterized by progressive neuron loses in memory-related brain structures

Some may have heavier periods, while others might have lighter ones than usual

Of note, individuals carrying the apolipoprotein E (APOE) 4 allelea well-known genetic risk factor for ADare at increased risk for developing ARIA, although the underlying mechanisms remain incompletely understood

DRUG INDUCED ACCUMULATION OF mtDNA DAMAGE Because mitochondria contain their own DNA, mitochondrial genome integrity is essential for organelle function

doi: 10.1186/s12958-019-0553-0 6 KumarTR