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Autophagy and intermittent fasting: The connection for cancer therapy

Hui KY, Fernandez-Hernandez H, Hu J, Schaffner A, Pankratz N, Hsu NY, et al

In humans, although spermatozoa are continuously produced with advanced paternal age, there is a growing body of evidence indicating that advanced paternal age is associated with negative impact on the quality of male germ cells [56], the number of Sertoli cells [57] and the number of Leydig cells [58]

2i,j), suggesting that this response is independent of oncogenic driver mutation and culture conditions 22

Moreover, supplementation with EPA and DHA has been shown to modulate nociceptive responses, potentially through activating the opioid system, offering benefits in neuropathic pain scenarios