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9-Tetrahydrocannabinol decreases extracellular GABA and increases extracellular glutamate and dopamine levels in the rat prefrontal cortex: an in vivo microdialysis study

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Besides, different clinical studies suggest that mTOR pathway inhibitor rapamycin can attenuate and prevent epileptogenesis, and could be effective in treating intractable epilepsy (Ostendorf and Wong 2015)