Visceral obesity, metabolic syndrome, insulin resistance and cancer
TP53 also influences ferroptosis sensitivity through other mechanisms, such as downregulating VKORC1L1 (vitamin K epoxide reductase complex subunit 1 like 1) in vitamin K metabolism [151] and inducing SAT1 (spermidine/spermine N1-acetyltransferase 1), an enzyme in polyamine catabolism that produces ROS [152]
In addition, tumors were photographed at day 0, 3, 6, 12, and 24 after the start of the trial
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[DOI] [PMC free article] [PubMed] [Google Scholar] 42.Park J.R., Lee H., Kim S.I., Yang S.R