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On the basis of previous experimental and clinical evidence, we speculated that there is a causal association between smoking and OAB, and smoking cessation may be insufficient to reverse the changes in bladder tissue structure, autonomic nerve damage, and urothelial cell degeneration resulting from long-term smoking

COPD, in particular, takes several decades to develop and severe symptoms dont usually manifest until later in life

One of those risks that can be reduced is incurring joint damage

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Group II (Nicotine-treated group), each mouse was treated with 2.5 mg/kg bwt/day of nicotine dissolved in 0.9% saline water via the i.p