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Basu N, Scheuhammer AM, Rouvinen-Watt K, Evans RD, Grochowina N, Chan LH

The exact inheritance pattern is still debated and believed to be polygenic and inherited from either parent

GK: Conceptualization, Funding acquisition, Investigation, Project administration, Resources, Supervision, Writing original draft, Writing review & editing

First, there is considerable heterogeneity in study designs, including wide variations in the dosage, bioavailability, and treatment duration of supplements (e.g., -3 PUFAs, collagen peptides), which complicates direct comparison and meta-analysis