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The authors highlighted mechanism-based combination strategiessuch as pairing HDACis with DNA-damaging agents, kinase inhibitors, immune checkpoint inhibitors, or proteasome inhibitorsthat can enhance antitumor responses and overcome resistance (209)
Once in heated paraffin, temporal bones are placed into a vacuum oven in paraffin for 24-48 hours to fully embed with paraffin, then placed into paraffin molds and allowed to harden into blocks at room temperature
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