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Mechanistically, ripasudil safeguarded membrane localization of CD59a, a MAC inhibitor highly expressed on hepatocytes, hindering the MAC formation (Ma et al., 2023)

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Long-term use is frequently associated with debilitating motor complications, such as dyskinesias and fluctuations in symptom control [6]

Instead of dispensing large amounts of product, the user applies only a few drops at a time, gently pressing the serum into the skin

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