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[28] Clinical significance [edit] In addition to their roles in cancer development and chemotherapeutic drug resistance, GSTs are implicated in a variety of diseases by virtue of their involvement with GSH

It is one of the body's strongest antioxidants and plays a key role in overall health, contributing to several glutathione benefits

Leucoanthocyanidins as intermediates in anthocyanidin biosynthesis in flowers of Matthiola incana R

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It has been established that all GSTs exist as dimeric proteins and have serine in the active site, however, DHARs and Lambda class GSTs are monomeric, and possess catalytic cysteine in active site (Wagner et al., 2002