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The in vivo results from showed that the total H3K4me3 levels were much higher, and those of H2AK119ub were much lower in the hippocampi of BHBA-treated mice as than those of the control mice, which was consistent with the in vitro results (Figures 2C,D)

Epidemiology 24 , 447453 (2013)

Clinical positioning and interpretive considerations for integrated multi-omics biomarkers Integrated multi-omics biomarkers are most credible when deployed to support decisions under defined clinical uncertainty, not as broad screening tools [5, 291]