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Protocol 1: seasonal allergic rhinitis (hay fever) Goal: Reduce seasonal allergy symptoms by stabilizing mast cells and modulating immune response before and during pollen season

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Handling and Aseptic Technique Proper handling is essential to maintain the integrity of BAC Water in research use: Withdrawals should be performed with sterile syringes or equipment The stopper and contact surfaces should be disinfected prior to each use Containers should be stored in accordance with laboratory guidelines and discarded if contamination is suspected While the solution is bacteriostatic, not bactericidal, adherence to aseptic technique is still required to minimize experimental variability and contamination risk

however, MADRS did not change significantly