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Vachharajani TJ, Work J, Issekutz AC, Granger DN

Medical coolers designed for insulin work well

HexR controls glucose-responsive genes and central carbon metabolism in neisseria meningitidis

Although vitamin B 12 deficiency is known to damage the myelin sheath covering cranial, spinal, and peripheral nerves, the biochemical processes leading to neurologic damage in vitamin B 12 deficiency are not yet fully understood (22)

Thats a mechanistically different target than NSAIDs (nonsteroidal anti-inflammatory drugs), or corticosteroids, which partly explains why the compound has attracted interest in cases where conventional anti-inflammatory approaches have failed or created downstream problems