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Additionally, although our murine model supports the proposed gene-environment interaction between ADORA2b deficiency and caffeine exposure, differences in RBC physiology between species or across humans (e.g., CYP2A enzymes) may affect translation to human transfusion outcomes

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When the oxidative stress [which is defined as an imbalance that leads to cell and tissue damage] becomes too high in the body, then we start seeing all kinds of diseases: Obesity, diabetes, hypertension, heart disease, metabolic disorderswe can even go as far as cancer, he states