Unser Take: Exzellentes Sicherheitsprofil, breite Evidenzbasis, gnstig
Since AAVs have been found to integrate within DSBs with high frequency [152], the coupling of CRISPR-Cas9 with AAVs as the delivery vector must be carefully evaluated before clinical translation [58, 153]
In the second part, these clusters are simultaneously evaluated with the socioeconomic development levels of provinces to understand whether there is a correlation between provincial profiles of ownership statuses and those development levels
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Furthermore, the inclusion of positive control groups reinforces the reliability and robustness of the findings