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As in other chronic respiratory diseases, excessive NE proteolytic activity causes tissue damage and disease progression by degrading proteins essential for maintaining alveolar structure (59, 62), increasing apoptosis and necrosis in the lungs, and activating senescence in airway epithelial cells (63, 64)

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height: 2.5 cm), topped with a ring-shaped holder where the sample dish is placed at a distance of 1 cm from the LED board and irradiated from below (Figure 1)

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