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Simultaneously, insulin resistance worsens dyslipidemia and hypertension, altering lipid metabolism and increasing sympathetic nervous system activity, which accelerates coronary artery disease progression (116)

Heme oxygenase 1 catalyzes the degradation of heme to free iron, biliverdin, and carbon monoxide (CO) thereby removing free heme which is pro-oxidant

Dexamethasone (Hameln Pharma GmbH) was pretreated for 16 h before adding FINs and inhibitors

Glutathione disulfide induces neural cell death via a 12-lipoxygenase pathway