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Abstract Despite its position as the first-line drug for treatment of type 2 diabetes mellitus, the mechanisms underlying the plasma glucose level-lowering effects of metformin (1,1-dimethylbiguanide) still remain incompletely understood

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The conclusion is that B vitamins can be used in treating neuroinflammation and promoting neuroregeneration, potentially serving as an effective therapy for PNI in humans.

The peptide does not work through a single receptor but rather through simultaneous modulation of multiple healing pathways

While these pharmaceuticals have been subjected to clinical trials, further investigation is imperative to ascertain their long-term safety and efficacy (Raulin et al., 2022