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The mechanism by which GLP-1 receptor agonists might contribute to pancreatitis risk remains unclear, but possibilities include effects on pancreatic enzyme secretion, changes in gallbladder motility leading to gallstone formation, or direct effects on pancreatic tissue

Gane, E

Melittin in BV has antibacterial properties (Elieh Ali Komi et al., 2018)

So the practical takeaway is not oral is better or SC is better. It is: pick one route, follow the documented per-dose figure for the vial you have, and keep the route constant so that whatever you observe is not confounded by a mid-stream route change

"Semaglutide 2.4 mg once a week in adults with overweight or obesity and type 2 diabetes." Lancet