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Many different physiological responses are mediated by different NOS isozymes such as eNOS, a vascular endothelial isoform, nNOS, a neuronal isoform, or iNOS, an inducible isoform that plays a role in immune defense mechanisms

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Clinical pen device: In trials, cagrilintide was delivered via Novo Nordisk's prefilled pen

These agents offer more targeted approaches than traditional immunosuppressants, but they still involve significant immune suppression and come with substantial costs and potential side effects

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