Intriguingly, another interesting research lead to the discovery of a differential role for IRSs in apoptosis, suggesting an antiapoptotic effect for IRS-2 [122] which is consistent with known differential roles of IGF-1 and insulin
How a B12 deficiency causes fatigue Your cells need B12 for proper function, and without the necessary amount, your red blood cell production decreases, which makes delivering oxygen to your cells more difficult
The use of B12 also provides neuroprotective and nerve-regeneration benefits, allowing it to alleviate neuropathic pain and muscular dysfunction by promoting health and muscle recovery
The combination of semaglutide and B12 offers a complementary approach where semaglutide regulates appetite and insulin release, whereas B12 maintains nerve function, supports red blood cell production, and converts foods into cellular energy
Other markers are not commonly measured either in clinical practice or in many clinical trials, making it difficult to interpret whether positive outcomes in some studies are due to correcting a deficiency or due to other pharmacological functions of B12