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183 The ADP-ribosylation of histones by PARP-1 induces the dissociation of nucleosomes, leading to the decompaction of chromatin

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The activation of target genes and the regulation of phase II detoxification enzymes, antioxidant enzymes, and drug transporters via the Keap1-Nrf2-ARE signalling pathway play crucial roles in mitigating oxidative damage and maintaining cellular homeostasis [96]

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Oncologist 15 , 360371 (2010)