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Studies designed to investigate BPC 157's effect on discogenic pain models, on nerve compression injuries, and on inflammatory markers in spinal tissue could provide the crucial data needed to move this field forward

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At 20 M, 10-gingerol, 6-shogaol, 8-shogaol, and 10-shogaol reduced the secretion of IL-1 on LPS-primed and ATP-activated IL-1 secretion in THP-1 macrophages with the inhibitory values of 102.2, 95.2, 63.6, and 46.5%, respectively (Ho & Chang, 2018)

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