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Pinnell SR, Yang H, Omar M, Riviere NM, DeBuys HV, Walker LC et al (2001) Topical L-ascorbic acid: percutaneous absorption studies

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In vitiligo, activated DCs migrate to regional lymph nodes, where they upregulate co-stimulatory molecules like CD80 and CD86, present melanocyte antigens to T cells, and provide the second signal for full activation

Since January 1, 2012 (the effective date of the regulations setting forth the expansion exception process), on average, we have received approximately one expansion exception request per year