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In addition, manganese oxide nanomaterials (MONs), including MnO 2 , Mn 2 O 3 , and Mn 3 O 4 , possess a similar GSH elimination property to Cu-based nanomaterials, and react with GSH along with the decomposition of MnO x into Mn 2+ for initiation of the Fenton-like reaction (Ding et al., 2020

This depletion compromises neuronal protection and may contribute to the onset or worsening of depressive symptoms, offering a potential explanation for why some treatments fail for certain patients

Yet, it has many roles and has been linked to impressive health benefits

Eryptosis hallmarks include PS exposure, cell size, intracellular calcium levels and hemolysis data (see Figure 4 and Supplementary Figures 1 5 for detailed data on each compound)

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