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The platform motion and tilting intervals were optimized to reduce medium backflow and to generate higher flow rates in one direction (unilateral flow) to avoid symmetrical bidirectional flow conditions that might affect barrier formation 32 For each motion cycle, the platform moved for 5 s until reaching the predetermined angle, which was then kept for 30 s to support the high flow rate

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Dose Range: 250500 mcg daily

Cheryl Bugailiskis, M.D