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The "Copper Uglies" A rare phenomenon called "copper uglies" involves skin appearing temporarily worse before improving

Total RNA was then reverse-transcribed into complementary DNA using PrimeScript RT Master Mix (Takara Biotechnology Co., Ltd.) according to the manufacturer's protocol

Malondialdehyde (MDA) levels are used as a biomarker to measure oxidative stress

The thioredoxin-1 system is essential for fueling DNA synthesis during T-cell metabolic reprogramming and proliferation

mexicana triggered a rapid accumulation of eosinophilic granulocytes (SSC high CD11b + SiglecF + cells) at the site of inoculation, detectable as early as day 6 post infection (p.i.) (Fig