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Given the known recurrence rate for endometriosis over time, without medical therapy, more women will likely have their endometriosis track toward disease progression rather than resolution

doi:10.3390/ijms27062876 PMID 40789979

Glutamate-cysteine ligase (GCL), the rate-limiting enzyme in glutathione production, remains active during supplementation

Given the triple-digit nanomolar affinity of the TRF1 TRFH :TIN2 TBM interaction 15 , an efficient competitor would likely need to be in the nanomolar affinity regime